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...for the 12th CeMEB Assembly is to discuss and learn more about measuring selection in the laboratory and in the wild...

Programme 23 - 25 September at Tjärnö

With reservation for changes...

Tuesday 23rd September

09.30 - 10.00 - Registration and coffee/tea

10.00 - 12.30, Big lecture hall

Kerstin Johannesson

Lotta Kvarnemo
Introduction to the meeting and the theme Selection


Session 1: Identifying and measuring selection in the wild 

Chair: Lotta Kvarnemo

Roger Butlin
The wonderful world of clines

Marina Rafajlovic
The dynamics of local adaptation of small partly isolated subpopulations

12.30 - 13.30 - Lunch

13.30 - 15.00 - Session 1, continue, Big lecture hall

Adam Jones
Confronting Challenges in the Measurement of Sexual Selection

Emily Rose
The effects of synthetic estrogen on total selection in the sex-role-reversed Gulf pipefish

15.00 - 15.40 - Coffee & tea 

15.40 - 16.50 - Session 1, continue, Big lecture hall

Chair: Eva Marie Rödström

Lightning talks - presentations of participating PhD students

  1. Angelica Ardehed
  2. Conny Sjöqvist
  3. Anna Abramova
  4. Ryosuke Kita
  5. Mårten Duvetorp
  6. Emily Rose
  7. Felix Mittermayer
  8. Kirsikka Sillanpää
  9. Simon Stenberg
  10. Li Ying Tan / Muhua Wang
  11. Henrik Christiansen
  12. Martin Zackrisson
  13. Sarah Flanagan
  14. Kamran Chabokdavan

16.50 - 18.20 - Group discussions I, Big lecture hall 

Identifying and measuring selection in the wild
Short introduction to the session: Kerstin Johannesson

Parallel discussions

  1. Studies of inheritance and selection is heavily biased in favour of annuals and short-lived perennials, which limits our understanding of life-history effects on patterns of selection and heritability. How can we detect and quantify natural selection in natural populations of long-lived species?
    Henrik Pavia - discussion facilitator
    Invited: Felicity Jones and Jeanine Olsen

  2. How to deal with the many low selection coefficients that we expect are very common in natural populations? Are these at all measurable in wild populations?
    Kerstin Johannesson - discussion facilitator
    Invited: Hunter Fraser and Stig Omholt

  3. What sorts of observational / experimental designs are required (i.e. what resources are required) to successfully measure selection in the wild? 
    Jon Havenhand - discussion facilitator
    Invited: Roger Butlin 

  4. How can we measure natural and sexual selection in the wild? 
    Lotta Kvarnemo - discussion facilitator
    Invited: Adam Jones and Silva Uusi-Heikkilä

18.30 - Dinner

19.30 - Pub, White dormitory

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Wednesday 24th September

08.00 - Breakfast

08.30 - 10.00, Big lecture hall

Session 2: How can we detect selection in the wild by looking at DNA sequence? 

Chair: Jonas Warringer

Hunter Fraser 
Adaptive evolution of gene expression

Ryosuke Kita
Linking selection on gene expression and fitness across diverse yeast strains


10.00 - 10.40 - Coffee & tea -
CeMEB PhD students meeting

10.40 - 12.30 - Session 2, continue, Big lecture hall

Felicity Jones
Title coming soon

Muhua Wang
Title coming soon

Anja Westram
Little evidence for similar genetic changes underlying repeated ecotype divergence in Littorina saxatilis

12.30 - 13.30 - Lunch

13.30 - 15.30 - Field excursions, incl coffee/tea

15.30 - 15.50 - presentation, Big lecture hall

Alexander Eiler
The marine - freshwater transition in streamlined bacteria

15.50 - 17.30 - Group discussions II, Big lecture hall

How can we detect selection in the wild by looking at DNA sequence?  
Short introduction to the session: Kerstin Johannesson

Parallel discussions:

  1. Why is allozyme variation not studied more extensively? (True candidates with known function and known 3D structure.) 
    Kerstin Johannesson - discussion facilitator
    Invited: Adam Jones and Jeanine Olsen
  2. Detecting selection from genetic information
    Questions to be discussed:
    > Detecting selection from DNA sequence is typically done without considering fitness, phenotypes or environment - is that a serious issue? How can fitness, phenotype, environmental and sequence data be integrated in the detection of selection? 

    > We tend to consider parts of genomes and the types of change that are well captured by short read sequencing. Other parts of the genome, e.g. subtelomeres or repetitive elements, are overlooked. We also tend to overlook most structural mutations. Is this a serious issue? How much do we miss?

    > Is it possible to distinguish loci under selection from intrinsic barriers to gene flow using genome scans? Bierne et al 2013, Current Zoology.
    Jonas Warringer & Carl André - discussion facilitators / two groups 
    Invited: Hunter Fraser & Felicity Jones

  3. How much selection is transferred to the next generation through epigenetic mechanisms? Many studies now show “transgenerational plasticity”: how important is selection on heritable differential gene-expression vs selection of different genotypes? 
    Jon Havenhand - discussion facilitator
    Invited: Stig Omholt and Silva Uusi-Heikkilä

  4. Pathogens and evolution. (How does parasites and diseases affect the selection on immune system related genes? Morbillivirus in seals as one example. (Virulence of parasites and host resistance an arms race.)) 
    Karin Hårding - discussion facilitator
    Invited: Roger Butlin


17.30 - 19.00 - Free time for spontaneous interactions

17.30 - 18.30 - CeMEB PhD students are invited to the Director's tea, Conference room, 3rd flour.

19.00 - Dinner & Pub

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Thursday 25th September

08.00  -  Breakfast

08.30 - 09.40, Big lecture hall

Session 3: Experimental selection - challenges and possibilities
Chair: Kerstin Johannesson

Silva Uusi-Heikkilä
What Can Selection Experiments Teach Us?

09.40 - 11.40 - Group discussions III, Big lecture hall
Including coffee & tea

Experimental selection - challenges and possibilities
Short introduction to the session: Kerstin Johannesson

Parallel discussions:

  1. Are laboratory experiments useful to predict selection/responses in the wild or should selection experiments rather be conducted in complex natural settings with disparate agents of selection? 
    Henrik Pavia - discussion facilitator
    Invited: Roger Butlin
  2. How to balance experimental efforts: Are there trade-offs between population sizes and number of generations? Can stochastic noise introduced by non-random mating and variation in reproductive output be compensated?
    Kerstin Johannesson - discussion facilitator
    Invited: Silva Uusi-Heikkilä
  3. How to separate selection on SNPs inside genes with epigenetic effects in experiments of selection lasting for a few generations? 
    Per Jonsson - discussion facilitator
    Invited: Hunter Fraser and Jeanine Olsen
  4. How to go from increase in frequency of a genetic or phenotypic variant - to establish true causality with regards to fitness change? How to reject drift, hitchhiking, and pleiotropy? 
    Jonas Warringer - discussion facilitator
    Invited: Felicity Jones and Stig Omholt

11.40 - 12.00, Big lecture hall

Concluding remarks and end of meeting, Kerstin Johannesson

12.00 - 13.00 - Lunch and departure

13.00 - 14.00  - Steering committee meeting together with Advisory board, Conference room

14.00 - 16.00 - Steering committee meeting, Conference room

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Page Manager: Eva Marie Rödström|Last update: 9/22/2014

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