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Poster winner #3

POSTER

Understanding evolutionarily ancient mechanisms of sponge-microbe interactions

Schmittmann, Lara(1), Fraune, Sebastian(2), Pita, Lucía(1), Hentschel, Ute(1,2)

(1) GEOMAR Helmholtz Centre for Ocean Research Kiel; (2) Christian-Albrechts-Universität zu Kiel

Presenter contact details: lschmittmann@geomar.de, Phone: +49 4316004488


Sponges (Porifera) are an evolutionarily ancient metazoan phylum with a fossil record dating back to the Precambrian. Their associated microbial communities are host species-specific and stable over space and time. Thus, the sponge-microbe association (termed “holobiont”) can provide valuable insights into ancient mechanisms of host-microbe interactions. While a growing body of –omics data has shed light on the composition and functional gene repertoire of bacterial symbionts, very little is known about the host side of the interaction. Therefore, we aim to develop the small and culturable breadcrumb sponge Halichondria panicea from the Baltic Sea into an experimentally tractable model system. The response of the sponge-host towards different bacteria will be investigated in vivo by combining experimental physiology with molecular approaches. First genomic and transcriptomic data revealed genes encoding for potential immune receptors that are similar to mammalian receptors. We investigate the involvement of proteins with a Toll/interleukin-1 receptor homologous (TIR) domain in recognition of MAMPs via homologous expression in vitro. This information will give insights into the evolution of the poriferan innate immune system which provides the mechanistic basis for host-microbe-interactions within the sponge holobiont.

Keywords: Halichondria panicea, holobiont, Toll/IL-1 receptors, experimental model system

Session: 5. Host-Microbe Coevolution in the Sea

Poster #: 17

Poster winner #3

Understanding evolutionarily ancient mechanisms of sponge-microbe interactions

Schmittmann, Lara(1), Fraune, Sebastian(2), Pita, Lucía(1), Hentschel, Ute(1,2)

(1)GEOMAR Helmholtz Centre for Ocean Research Kiel; (2)Christian-Albrechts-Universität zu Kiel

Presenter contact details: lschmittmann@geomar.de, Phone: +49 4316004488

ABSTRACT

Page Manager: Eva Marie Rödström|Last update: 5/29/2018
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